Abstract Search

hrp0084fc1.3 | Adrenal | ESPE2015

Aldosterone and Mineralocorticoid Receptor as Inducers of Immune Markers in Peripheral Blood Mononuclear Cells: Beyond Elevating Blood Pressure

Vecchiola Andrea , Munoz-Durango Natalia , Cifuentes Mariana , Lagos Carlos , Fuentes Cristobal , Gonzalez Luis-Martin , Ortiz David , Carvajal Cristian , Tapia-Castillo Alejandra , Valdivia Carolina , Martinez-Aguayo Alejandro , Allende Fidel , Solari Sandra , Bancalari Rodrigo , Garcia Hernan , Campino Carmen , Baudrand Rene , Kalergis Alexis , Fardella Carlos E

Background: In vitro studies suggest a broader role for aldosterone, beyond elevating blood pressure. Clinical data support the notion that aldosterone can directly alter the function of the immune system and can participate in low-grade inflammation which leads to blood pressure elevation and end organ damage.Objective and hypothesis: To assess in humans, whether aldosterone plasma levels and mineralocorticoid receptor (MR) expression associate...

0 shares

ESPE Abstracts

Aldosterone and Mineralocorticoid Receptor as Inducers of Immune Markers in Peripheral Blood Mononuclear Cells: Beyond Elevating Blood Pressure

BiosciAbstracts